Tag: pentr d topo

Targeting CD99 compromises the oncogenic effects of the chimera EWS-FLI1 by inducing re-expression of zyxin and inhibition of Gli1 activity

Targeting CD99 compromises the oncogenic effects of the chimera EWS-FLI1 by inducing re-expression of zyxin and inhibition of Gli1 activityTargeting CD99 compromises the oncogenic effects of the chimera EWS-FLI1 by inducing re-expression of zyxin and inhibition of Gli1 activity

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Ewing sarcoma (EWS), a extremely aggressive pediatric tumor, is pushed by EWS-FLI1, an oncogenic transcription issue that remodels the tumor genetic panorama. Epigenetic mechanisms play a pivotal function in EWS

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Non-HLA antibodies targeting angiotensin II type 1 receptors and endothelin-1 type A receptors impair endothelial repair via a β2-arrestin link to the mTOR pathway

Non-HLA antibodies targeting angiotensin II type 1 receptors and endothelin-1 type A receptors impair endothelial repair via a β2-arrestin link to the mTOR pathwayNon-HLA antibodies targeting angiotensin II type 1 receptors and endothelin-1 type A receptors impair endothelial repair via a β2-arrestin link to the mTOR pathway

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Useful non-HLA antibodies (antibodies to non-human leukocyte antigens) focusing on the G protein-coupled receptors angiotensin II kind 1 receptor (AT1R) and endothelin-1 kind A receptor (ETAR) are implicated within the

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Isolation and characterization of a novel GRP78-specific single-chain variable fragment (scFv) using ribosome display method

Isolation and characterization of a novel GRP78-specific single-chain variable fragment (scFv) using ribosome display methodIsolation and characterization of a novel GRP78-specific single-chain variable fragment (scFv) using ribosome display method

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Glucose-regulated protein 78 (GRP78) is a well-characterized endoplasmic reticulum (ER) chaperon steadily overexpressed on the floor of tumor cells and related to tumor survival, metastasis, and chemoresistance. Therefore, potential GRP78

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