Protein ubiquitination is a key post-translational modification regulating a variety of organic processes. Ubiquitination entails the covalent attachment of the small protein ubiquitin to a lysine of a protein substrate.
Protein ubiquitination is a key post-translational modification regulating a variety of organic processes. Ubiquitination entails the covalent attachment of the small protein ubiquitin to a lysine of a protein substrate.
Glucose-regulated protein 78 (GRP78) is a well-characterized endoplasmic reticulum (ER) chaperon steadily overexpressed on the floor of tumor cells and related to tumor survival, metastasis, and chemoresistance. Therefore, potential GRP78